Earlier this year, the Centers for Disease Control and Prevention projected the number of undiagnosed cases of Lyme disease to be 10-fold higher than previously believed. Of the newly identified 300,000 people infected each year, between 30,000 and 60,000 fall into the category of having chronic Lyme, where symptoms persist despite zero evidence that the pathogen remains in their bodies. With the support of a Lyme Research Alliance grant, University Distinguished Professor of Biology Kim Lewis in the College of Science is exploring alternative approaches to curing chronic Lyme disease. We asked him to explain his research goals and why now is the perfect time to find a cure.